Canine osteosarcoma is the most common bone cancer in dogs and often progresses quickly. This in‑depth guide explains how the disease develops, the early warning signs to watch for, how veterinarians diagnose it, and the treatment options available—including surgery, chemotherapy, and palliative care. You’ll also learn about prognosis factors, pain management strategies, and ways to support your dog’s comfort and mobility throughout their care journey. This article is designed to help dog owners understand the condition and make informed decisions with their veterinary team.